Ogawa Lab Team Surface

We believe everything we do can challenge the status quo.

Dr Takahiro Ogawa delivered a keynote lecture in the International Academy of Ceramic Implantology.

Video intro on Novel Zr Surface

Ogawa Lab Team Surface: Representative publications in the recent years

For the complete list of publications, please visit Google Scholar.

Park G, Matsuura T, Komatsu K, Ogawa T. Optimizing implant osseointegration, soft tissue responses, and bacterial inhibition: A comprehensive narrative review on the multifaceted approach of the UV photofunctionalization of titanium. J Prosthodont Res 2024;

Komatsu K, Matsuura T, Cheng J, Kido D, Park W, Ogawa T. Nanofeatured surfaces in dental implants: contemporary insights and impending challenges. Int J Implant Dent 2024;10:34.

Matsuura T, Komatsu K, Cheng J, Park G, Ogawa T. Beyond microroughness: novel approaches to navigate osteoblast activity on implant surfaces. Int J Implant Dent 2024;10:35.

Komatsu K, Matsuura T, Suzumura T, Ogawa T. Genome-wide transcriptional responses of osteoblasts to different titanium surface topographies. Mater Today Bio 2023;23:100852.

Komatsu K, Matsuura T, Ogawa T. Achieving complete human gingival fibroblast collagen coverage on implant abutments through vacuum ultraviolet (VUV) photofunctionalization. International Journal of Oral and Maxillofacial Implants. Int J Oral Maxillofac Implants. Online published.

Kido D, Komatsu K, Suzumura T, Matsuura T, Cheng J, Kim J, et al. Influence of Surface Contaminants and Hydrocarbon Pellicle on the Results of Wettability Measurements of Titanium. Int J Mol Sci 2023;24:

Suzumura T, Matsuura T, Komatsu K, Sugita Y, Maeda H, Ogawa T. Vacuum Ultraviolet (VUV) Light Photofunctionalization to Induce Human Oral Fibroblast Transmigration on Zirconia. Cells 2023;12:2542.

Suzumura T, Matsuura T, Komatsu K, Ogawa T. A Novel High-Energy Vacuum Ultraviolet Light Photofunctionalization Approach for Decomposing Organic Molecules around Titanium. Int J Mol Sci 2023;24:

Matsuura T, Komatsu K, Choi K, Suzumura T, Cheng J, Chang TL, et al. Conditional Mitigation of Dental-Composite Material-Induced Cytotoxicity by Increasing the Cure Time. J Funct Biomater 2023;14:

Matsuura T, Stavrou S, Komatsu K, Cheng J, Pham A, Ferreira S, et al. Disparity in the Influence of Implant Provisional Materials on Human Gingival Fibroblasts with Different Phases of Cell Settlement: An In Vitro Study. Int J Mol Sci 2023;25:

Kitajima H, Hirota M, Osawa K, Iwai T, Saruta J, Mitsudo K, et al. Optimization of blood and protein flow around superhydrophilic implant surfaces by promoting contact hemodynamics. J Prosthodont Res 2022;

Kitajima H, Komatsu K, Matsuura T, Ozawa R, Saruta J, Taleghani SR, et al. Impact of nano-scale trabecula size on osteoblastic behavior and function in a meso-nano hybrid rough biomimetic zirconia model. J Prosthodont Res 2023;67:288-299.

Saruta J, Ozawa R, Okubo T, Taleghani SR, Ishijima M, Kitajima H, et al. Biomimetic Zirconia with Cactus-Inspired Meso-Scale Spikes and Nano-Trabeculae for Enhanced Bone Integration. Int J Mol Sci 2021;22:

Sugita Y, Okubo T, Saita M, Ishijima M, Torii Y, Tanaka M, et al. Novel Osteogenic Behaviors around Hydrophilic and Radical-Free 4-META/MMA-TBB: Implications of an Osseointegrating Bone Cement. Int J Mol Sci 2020;21:

Our Mission

Pursuing the surface of the century:

We create new implant surfaces with astonishing biological performance and unprecedented surface appearance employing novel biomimetic idea and ground-breaking technology and responsibly transfer them to relevant industry and market to substantially advance patient care in the field of implant dentistry and orthopedic surgery.

Our vision

Overcoming 30 years of stagnation of implant surfaces:

Implant surfaces have not improved in the past 30 years; no implant is better than the other. We envision that in the near future dentists and doctors will be able to find and choose the best implants with full confidence and evidence. Likewise, all patients in the wold can receive the best implants with lower cost and higher accessibility.

Zr outperforming Ti

Creating a brand-new zirconia surface that outperforms current titanium surfaces.

Osseointegrating bone cement

Developing an orthopedic bone cement with reduced toxicity and bioinert nature after 60 years of stagnation in the field. Currently available bone cement products are cytotoxic and considered biotolerant, which causes significant complications and a high percentage of revision surgery.

UV-photo-activation

Developing photo-technology to bring dental and orthopedic implants to even higher levels. UV-photo-activation project has come to the never-been-seen stage to maximize doctors' and patients' benefits.

Titanium in the rough

Pursuing a titanium surface of the century by creating an unparalleled surface morphology and astounding biological performance. This conceptual image is based on the biological principle and biomechanical rationale, signaling an emerging revolution in implant dentistry.